The primary goal of SNAP is to reduce the frequency of severe asthma attacks and improve the quality of life of patients with asthma.
Satisfactory asthma control improved from 9.4% with the 1st visit to 72% on the 6th visit. Return rate to the Children's Emergency reduced from 69% on the 1st visit to 12% on the 6th visit.
* A database for high-risk asthma patients was developed by KKH Research Center and houses all the data of all high risk patients in KKH
* Recruitment of high-risk asthma patient from August 2001 to Jan 2009, with a total of 3307 patients.
Results after outpatient follow-up
Indictors
Visit1
Visit 2
Visit 3
Visit 4
Visit 5
Visit 6
Absent from school 34.5% 10.2% 9.91% 11.4% 10.4% 9.7%
Parents work loss 15% 4.7% 3.93% 4.08% 4.09% 5.01%
Days with wheeze/cough/SOB 75% 37.% 33% 32% 29.4% 30%
Nights with wheeze/cough/SOB 77.6% 34.4% 30.6% 29% 27% 27.5%
Activity stopped 42% 16% 14% 12% 14.4% 14.3%
Indictors
Visit1 Visit 2
Visit 3
Visit 4
Visit 5
Visit 6
Respiratory infection 89.7% 44.9% 48% 46% 44% 44.7%
Need for acute care 82.9% 22.7% 24% 23% 21% 24%
Visit GP/ OPS 65.8% 19.9% 22 % 22% 18.3% 22.6%
Visit Emergency Department 68.9% 12.3% 11.8% 11.9% 11% 11.9%
Hospitalization 63% 10.% 8.6% 9.4% 8.3% 8.4%
Compliance with Preventer/Controller 17.4% 71.6% 68.6% 69.6% 72.4% 1.4%
Satisfactory asthma control 9.4% 66.9% 68% 69.3% 72% 71.6%
Lymphoma, Neuroblastoma, Sarcoma, Besides malignant and non-malignant blood disorders
KKH’s Children’s Cancer Centre is one of the largest paediatric cancer centers in South-East Asia, treating 70% of childhood cancers in Singapore. Each year, the center sees between 70-90 paediatric cancer cases of which 40% are leukaemia.
Childhood cancer is the second major cause of death among children in Singapore. There are between 130 –150 newly diagnosed cases each year. Acute Lymphoblastic leukemia (ALL) is the most common malignancy in children and adolescent, representing 41% of all childhood cancer causes.
Here at KKH, the outcome for ALL has climbed steadily from 40% in the 80’s to 60% in the 90’s and 80% in 2000’s. Present chemotherapy regime produces more than 80% 5-year survival rates in Singapore. This is comparable with world-renowned children cancer centers. Studies are ongoing to refine protocol to decrease treatment in those with standard risk ALL to minimize late effects of treatment. While those with high risk ALL requires consolidation treatment, which includes allogeneic haemapoietic stem transplant.
5 yrs OS: 83.4% N = 222
Our Children’s Cancer Centre also uses allogenic haematopoietic sten cell transplant as a form of treatment for the following cancers:
Our survival rates for allogeneic haematopoietic stem cell transplant stands at 70%. These are comparable to the best centers in the world.
Our center is one of the participating centers for umbilical cord blood transplant in Eurocord Registry. The Singapore Public Cord Blood Bank is sited in KKH.
